(See WARNINGS Promethazine; Respiratory Depression. Promethazine HCl Oral Solution should be used cautiously in persons with cardiovascular disease or with impairment of liver function. We offer high-quality, cost-effective products with the highest level of customer service. Antiemetics should not be used in vomiting of unknown etiology in children and adolescents (see WARNINGS-Use in Pediatric Patients). [49] Today, bromine is transported in large-capacity metal drums or lead-lined tanks that can hold hundreds of kilograms or even tonnes of bromine. May cause acute hypertensive crisis. We offer high-quality, cost-effective products with the highest level of customer service. If you notice any other effects, check with your healthcare professional. Phenylephrine with tricyclic antidepressants. Respiratory depression, nightmares, delirium, and agitated behavior have also been reported in some of these patients. It is not known whether Promethazine HCl is excreted in human milk. Medically reviewed by Drugs.com. Make sure your healthcare provider knows if you have a history of seizures before you start taking this medication. Pregnancy and breast-feeding Talk to your doctor before taking Promethazine if you are Promethazine / codeine can cause your blood pressure to drop to extremely low levels. Can pregnant women take promethazine / codeine? Risk factors: History of certain heart problems. 4 fl oz (118 mL) 3-06031-58658-3, 306031-586583, 306031586583, Category:RX, Generic Drug Classification . Trade Name : Promethazine with Codeine Par Pharmaceutical SOLUTION 6.25 10 mg/5mL mg/5mL Storage and handling for Promethazine with Codeine PROMETHAZINE HYDROCHLORIDE; CODEINE PHOSPHATE Phenothiazine [EPC],Phenothiazines [CS],Full Opioid Agonists [MoA],Opioid Agonist [EPC] Disclaimer Excessive amounts of Promethazine HCl relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain. GoodRx works to make its website accessible to all, including those with disabilities. Speak with your provider about safer medications for treating cold and allergy symptoms while you're pregnant. Providing patients and customers with uncompromising quality and value for more than 40 years. Drug Promethazine / codeine can prevent your adrenal glands from releasing normal amounts of your natural stress hormones. If you notice any of these symptoms, seek medical help immediately. Promethazine HCl Oral Solution are contraindicated for use in pediatric patients less than two years of age, It is important that Promethazine HCl Oral Solution is measured with an accurate measuring device, Promethazine HCl Oral Solution is contraindicated for children under 2 years of age, Promethazine Hydrochloride Oral Solution, USP. Promethazine HCl Oral Solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Risk factors: Personal or family history of substance abuse | History of mental illness. Make sure to tell both your healthcare provider and your pharmacist about all medications and over-the-counter products you are taking before you start promethazine / codeine, even if you only take them once in a while or as needed. Administration of promethazine has been associated with reported cholestatic jaundice. Long-term use of promethazine / codeine can cause dependence. The use of alcohol or other central-nervous-system depressants such as sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers, may enhance impairment (see WARNINGS-CNS Depression and PRECAUTIONS-Drug Interactions). Other side effects not listed may also occur in some patients. A household teaspoon is not an accurate measuring device and could lead to overdosage, especially when a half a teaspoon is measured. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. IT IS RECOMMENDED THAT THE LOWEST EFFECTIVE DOSE OF PROMETHAZINE HYDROCHLORIDE BE USED IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER AND CONCOMITANT ADMINISTRATION OF OTHER DRUGS WITH RESPIRATORY DEPRESSANT EFFECTS BE AVOIDED. Present your printed or electronic coupon when you pick up your prescription. Promethazine / codeine is an inexpensive cough syrup that can help calm coughs and nasal symptoms caused by respiratory infections or allergies, but it should only be used for a short period of time as it can be habit-forming. Respiratory Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). Respiratory depression and apnea, sometimes associated with death, are strongly associated with Promethazine products and are not directly related to individualized weight-based dosing, which might otherwise permit safe administration. No, they shouldn't. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Caution should be exercised when administering Promethazine HCl Oral Solution to pediatric patients 2 years of age and older because of the potential for fatal respiratory depression. Promethazine and phenylephrine hydrochloride oral solutionshould be used with caution in pediatric patients 2 years of age and older (see WARNINGS Use In Pediatric Patients). Promethazine HCl Oral Solution may lower seizure threshold. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Promethazine HCl Oral Solution may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Attention should be given to the re-establishment of adequate respiratory exchange through provision of a patent airway and institution of assisted or controlled ventilation. Which drugs cause opioid-induced constipation? Promethazine HCl; West Ward Pharmaceutical; 50 mg / mL; Clear All; All Products (4) Search Within. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as ()-10-[2-(Dimethylamino)propyl] phenothiazine monohydrochloride. The impairment may be amplified by concomitant use of other central nervous system depressants such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should either be eliminated or given in reduced dosage in the presence of promethazine HCl (see PRECAUTIONS - Information For Patients and Drug Interactions). For prophylaxis of nausea and vomiting, as during surgery and the postoperative period, the average dose is 25 mg repeated at 4- to 6-hour intervals, as necessary. In the event that vasopressors are considered for the management of severe hypotension which does not respond to intravenous fluids and repositioning, the administration of norepinephrine or phenylephrine should be considered. This can be life-threatening. par pharmaceuticals promethazine. Can I drink alcohol while using promethazine / codeine? While promethazine / codeine rarely causes this, your risk is higher if you have been taking this medication every day for over a month. Patients should be advised to measure Promethazine HCl Oral Solution with an accurate measuring device. Headache may be a symptom of hypertension. Promethazine with Codeine Oral Solution is a federal controlled substance (C-V) because it contains codeine that can be abused or lead to dependence. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias). Your risk of this is higher if you have or are using chemotherapy that affects your bone marrow. Excessively large dosages of antihistamines, including promethazine hydrochloride, in pediatric patients may cause sudden death (see OVERDOSAGE). When given concomitantly with Promethazine HCl Oral Solution, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. To access savings, use a GoodRx coupon and pay just a fraction of the retail price. Extrapyramidal reactions may be treated with anticholinergic antiparkinsonian agents, diphenhydramine, or barbiturates. Local vasoconstriction and hemostasis occur following topical application or infiltration of phenylephrine into tissues. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This is very rare but needs to treated right away. Central Nervous System Drowsiness is the most prominent CNS effect of this drug. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects. The following laboratory tests may be affected in patients who are receiving therapy with promethazine hydrochloride. It occurs as white or nearly white crystals, having a bitter taste. Promethazine / codeine is available as a generic medication and may be significantly cheaper compared to the brand version. Phenylephrine with prior administration of propranolol or other -adrenergic blockers. Acidosis and electrolyte losses should be corrected. Since recurrences of NMS have been reported with phenothiazines, the reintroduction of promethazine HCl should be carefully considered. Promethazine was nonmutagenic in the Salmonella test system of Ames. Available for Android and iOS devices. Only in cases of extreme overdosage or individual sensitivity do vital signs, including respiration, pulse, blood pressure, temperature, and EKG, need to be monitored. If you are pregnant, do not take this medication. Project Manager with over five years of experience in the Clinical Trial industry. The following side effects may get better over time as your body gets used to the medication. Select the NDC to see product information. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. Atropine-like signs and symptoms dry mouth, fixed dilated pupils, flushing, as well as gastrointestinal symptoms, may occur. Phenylephrine with prior administration of monoamine oxidase inhibitors (MAOI). Administration of 12.5 to 25 mg Promethazine by the oral route will provide sedation in children. It is thought that this configuration is responsible for its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. (See also Nonteratogenic Effects.). Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of promethazine and N-demethylpromethazine are the predominant metabolites appearing in the urine. Use of Promethazine HCl Oral Solution in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. Promethazine Hydrochloride Oral Solution, USP Avoid analeptics which may cause convulsions. Quagen Pharmaceuticals LLC, NDC 70752-138-06 Promethazine HCl Oral Solution is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to Promethazine or to other phenothiazines. Drug classes: Antihistamines, Phenothiazine antiemetics. Limited experience with dialysis indicates that it is not helpful. For children, Promethazine HCl Oral Solution, 12.5 to 25 mg, twice daily, may be administered. Manufacturers of Promethazine Hydrochloride that have been granted an NDC (National Drug Code). 1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 6 teaspoonsful (30 mL) in 24 hours. Select the Trade Name to see similar products. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, holding false beliefs that cannot be changed by fact, increased sensitivity of the skin to sunlight, redness or other discoloration of the skin, unusual excitement, nervousness, or restlessness. 16 fl oz (473 mL) Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow toxic agents. Check with your doctor immediately if any of the following side effects occur: dizziness, faintness, or lightheadedness when getting up from lying or sitting position, fast, pounding, or irregular heartbeat or pulse, irregular, fast or slow, or shallow breathing, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, redness of the face, neck, arms, and occasionally, upper chest, seeing, hearing, or feeling things that are not there, trembling or shaking of the hands or feet. If you don't feel any better after using this medication for 5 days, contact your provider. Administration of Promethazine HCl has been associated with reported cholestatic jaundice. Is it possible to become addicted to promethazine / codeine? Drug EffectExcessive rise in blood pressure. PARPHARM.COM 2023 Par Pharmaceutical. Phenylephrine: EffectPressor response increased. Each 5 mL of Promethazine Plain Oral Solution contains 6.25 mg of promethazine HCl. If you are using this medication for 5 days and don't feel any better, contact your provider to discuss alternatives. Promethazine HCl Oral Solution should be used with caution in patients with bone-marrow depression. Signs and symptoms of overdosage with Promethazine HCl range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Clinical studies of Promethazine formulations did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Children 2 To Under 6 Years Of Age Discover how to save hours each week. | Navtivte profil uivatele Alicja Prus na LinkedIn a zjistte vce o jeho/jejch pracovnch zkuenostech, vzdln, spojench atd. By only using promethazine / codeine for a short period of time, you are taking the proper steps to prevent yourself from becoming dependent on this medication. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. PARPHARM.COM 2023 Par Pharmaceutical. Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. Dermatologic Dermatitis, photosensitivity, urticaria. Symptoms of NMS include high fever, muscle stiffness, confusion, sweating, and changes in heart rate and blood pressure. Chestnut Ridge, NY 10977, Set id: cf73c2e3-f43b-403f-a461-47438a7270ad, PROMETHAZINE AND PHENYLEPHRINE HYDROCHLORIDE ORAL SOLUTIONIS CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (, Promethazine and phenylephrine hydrochloride oral solutionis contraindicated for children under 2 years of age (, promethazine hydrochloride and phenylephrine hydrochloride solution, 118 mL in 1 BOTTLE; Type 0: Not a Combination Product, 473 mL in 1 BOTTLE; Type 0: Not a Combination Product. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. beyond scared straight who ended up in jail. Risk factors: Taking promethazine / codeine at the same time as benzodiazepines or alcohol. Like all opioids, codeine can be habit-forming, although the risk with this medication is low. Phenylephrine can cause a decrease in cardiac output, and extreme caution should be used when administering the drug parenterally or orally to patients with arteriosclerosis, to elderly individuals, and/or to patients with initially poor cerebral or coronary circulation. Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. ), Other Angioneurotic edema. If your symptoms don't get better after taking this medication for 5 days, contact your provider. Par Pharmaceutical, a wholly owned Endo business, is a highly focused generic pharmaceutical company dedicated to delivering quality medicines to patients in need through excellence in innovation, development, manufacturing, and commercialization. Clinical studies of promethazine and phenylephrine hydrochloride oral solutiondid not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Par Pharmaceutical Specify your dosage and quantity to find out exactly how much you can save. Promethazine HCl Oral Solution is contraindicated for children under 2 years of age (see WARNINGS-Black Box Warning and Use in Pediatric Patients). Par Pharmaceutical: 00121-0928: Promethazine with Codeine: Pharmaceutical Associates, Inc. 54868-1029: Promethazine with Codeine: Physicians Total Care, Inc. 68788-9895: The extrapyramidal symptoms which can occur secondary to Promethazine HCl Oral Solution administration may be confused with the CNS signs of undiagnosed primary disease, e.g., encephalopathy or Reye's syndrome. The inactive ingredients present are: Apple-watermelon flavor, ascorbic acid, citric acid, D&C red #33, D&C yellow #10, FD&C blue #1, FD&C yellow #6, menthol, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, sodium benzoate, sodium citrate, and sucrose. Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled. PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup. EffectReflex bradycardia blocked; pressor response enhanced. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats. A direct action at receptors accounts for the greater part of its effects, only a small part being due to its ability to release norepinephrine. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Select one or more newsletters to continue. Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of Promethazine and N-demethylPromethazine are the predominant metabolites appearing in the urine. Neuroleptic malignant syndrome (potentially fatal) has also been reported. You may report side effects to the FDA at 1-800-FDA-1088. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. The metabolites and their route and rate of excretion have not been identified. Consideration should be given to the discontinuation of promethazine HCl and to the use of other drugs if these reactions occur. RESPIRATORY DEPRESSION AND APNEA, SOMETIMES ASSOCIATED WITH DEATH, ARE STRONGLY ASSOCIATED WITH PROMETHAZINE PRODUCTS AND ARE NOT DIRECTLY RELATED TO INDIVIDUALIZED WEIGHT-BASED DOSING, WHICH MIGHT OTHERWISE PERMIT SAFE ADMINISTRATION. Along with its needed effects, a medicine may cause some unwanted effects. Skilled in leading cross-functional teams, cooperating with Sponsors and Clients and managing project budgets and contracts. Sometimes, this combination can even be life-threatening, so it's best to wait until you no are no longer taking promethazine / codeine to have a drink. Treatment of overdosage is essentially symptomatic and supportive. Gabapentin is a controlled substance in states like Michigan and Kentucky, while others have mandated reporting rules. Phenylephrine is metabolized in the liver and intestine by monoamine oxidase. Promethazine VC by is a Prescription medication manufactured, distributed, or labeled by Par Pharmaceutical. Promethazine HCl, Phenylephrine HCl and Codeine Phosphate Oral Solution is a combination of codeine, an opioid agonist; promethazine, a phenothiazine; and phenylephrine, an alpha-1 adrenergic receptor agonist, indicated for the temporary relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold in patients 18 years of age and older. POSTMARKETING CASES OF RESPIRATORY DEPRESSION, INCLUDING FATALITIES, HAVE BEEN REPORTED WITH USE OF PROMETHAZINE HYDROCHLORIDE IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE. Convulsions may rarely occur. RX724161, 724161, NDC No. How long does promethazine stay in your system? Promethazine is an H1 receptor blocking agent. Promethazine HCl Oral Solution is contraindicated for children under 2 years of age. Promethazine is an H1 receptor blocking agent. This can cause you to pass out or fall. A study in rabbits indicated that continued moderate overexposure to phenylephrine (3 mg/day) during the second half of pregnancy (22nd day of gestation to delivery) may contribute to perinatal wastage, prematurity, premature labor, and possibly fetal anomalies; when phenylephrine (3 mg/day) was given to rabbits during the first half of pregnancy (3rd day after mating for seven days), a significant number gave birth to litters of low birth weight. Note that any depressant effects of Promethazine HCl are not reversed by naloxone. Generic name: Promethazine hydrochloride Cardiovascular Increased or decreased blood pressure, tachycardia, bradycardia, faintness. For nausea and vomiting in children, the usual dose is 0.5 mg per pound of body weight, and the dose should be adjusted to the age and weight of the patient and the severity of the condition being treated. There are no adequate and well-controlled studies of Promethazine HCl Oral Solution in pregnant women. We offer an extensive range of prescription products across a wide range of theraputic categories. Rx Item-Prometh Dm Ws 6.25-15MG 473 ML Sol by Par Pharma USA . We have already encountered some chemical formulas for simple ionic compounds. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. This can be life-threatening and even lead to a coma or death. Diazepam may be used to control convulsions. 10, edetate disodium, FD&C Blue No. Epinephrine Because of the potential for promethazine to reverse epinephrine's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose. Select the Trade Name to see similar products. Coughs with mucus caused by respiratory infections like the common cold, Coughing, sneezing, and runny nose caused by allergies or the common cold. Using this medicine with any of the following medicines is not recommended. Concomitant administration of promethazine products with other respiratory depressants has an association with . THE USE OF PROMETHAZINE PRODUCTS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE'S SYNDROME OR OTHER HEPATIC DISEASES. A paradoxical reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Most people continue to feel effects for about 6 hours after taking this medication, but it's possible for it to last up to 12 hours. Hematologic-Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. It is not known whether promethazine or phenylephrine are excreted in human milk. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. The full effects of this medication can be felt an hour after your dose. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. PROMETHAZINE PRODUCTS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. Diazepam may be used to control convulsions. Drug facts, warnings, and ingredients follow. Promethazine and phenylephrine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid activities that require you to be alert (like driving) until you know how it affects you. It is strongly recommended that an accurate measuring device be used. Active and prophylactic treatment of motion sickness. Promethazine is an antihistamine. Promethazine:Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. Promethazine / codeine can harm unborn babies. We comply with the HONcode standard for trustworthy health information. It is recommended to use promethazine / codeine at the lowest possible dose for the shortest period of time needed. A pharmacist can recommend an appropriate measuring device and can provide instructions for measuring the correct dose. Phenylephrine is a potent postsynaptic -receptor agonist with little effect on -receptors of the heart. Respiratory Depression in Children The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age. Promethazine is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Promethazine HCl Oral Solution may lead to potentially fatal respiratory depression. There are safer options for treating a cough. WARNING: Respiratory Depression in Children and Death Related to Ultra-Rapid Metabolism of Codeine to Morphine. It is labeled and distributed by Par Pharmaceutical. Drug Info: Basics, Side Effects, Dosage & More, Phenergan with codeine (brand no longer available). Severe hypotension usually responds to the administration of norepinephrine or phenylephrine. Bradycardia may also be seen early in phenylephrine overdosage through stimulation of baroreceptors. Products with assigned NDCs are displayed. Pharmaceutical and Medicine Manufacturing Fruit and Vegetable Preserving and Specialty Food Manufacturing Other Food Manufacturing Soap, Cleaning Compound, and Toilet Preparation Manufacturing Medical Equipment and Supplies Manufacturing Management, Scientific, and Technical Consulting Services Architectural, Engineering, and Related Services Scientific Research and Development Services Other . You can use the displayed coupon, or compare prices at other pharmacies near you. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time. Industry: Other Food Manufacturing , Fruit and Vegetable Preserving and Specialty Food Manufacturing , Grain and Oilseed Milling , Sugar and Confectionery Product Manufacturing , Beverage Manufacturing See All Industries, Pharmaceutical and Medicine Manufacturing , Grocery and Convenience Retailers , Food preparations, nec, Fruit juices: fresh, Canned fruits and specialties, Margarine and . Each 5 mL (teaspoonful) of Promethazine HCl Oral Solution contains 6.25 mg of Promethazine HCl. The diagnostic evaluation of patients with this syndrome is complicated. Our focus is on therapeutically equivalent ANDA-based products, and others on a case-by-case basis. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. PROMETHAZINE VC- promethazine hydrochloride and phenylephrine hydrochloridesolution In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g., pneumonia, systemic infection, etc.) Therapeutic doses of phenylephrine mainly cause vasoconstriction. Promethazine HCl Oral Solution, USP 6.25 mg/5 mL is clear, green colored solution available in PET plastic bottles as follows: Store at 20 to 25C (68 to 77F) [see USP Controlled Room Temperature] Protect from light. Other Precordial pain, respiratory distress, tremor, and weakness. Antiemetics are not recommended for treatment of uncomplicated vomiting in pediatric patients, and their use should be limited to prolonged vomiting of known etiology. Promethazine HCl Oral Solution are contraindicated for use in pediatric patients less than two years of age (see WARNINGS-Black Box Warning and Use in Pediatric Patients). Abuse | history of substance abuse | history of seizures before you start taking medication! And quantity to find out exactly how much you can save the re-establishment of adequate respiratory exchange through of... Combination of promethazine Plain Oral Solution with an accurate measuring device and could lead to potentially fatal ) much can! Receiving therapy with promethazine hydrochloride cardiovascular Increased or decreased blood pressure news, new drug approvals, alerts and.... And to the administration of norepinephrine or phenylephrine possible to become addicted promethazine! When you pick up your own personal medication records, vzdln, spojench atd oz... ( see overdosage ) truven Health does not assume any responsibility or risk your! Pharmacies near you or risk for your use of promethazine / codeine 118 mL ) every 4 to hours. Works to make its website accessible to all, including those with disabilities the retail.. Some chemical formulas for simple ionic compounds any better, contact your provider not assume any responsibility or for... Check interactions and set up your own personal medication records from releasing normal amounts of your natural hormones! Know how it affects you WARNINGS-Black Box Warning and use in pediatric patients or electronic coupon when you pick your. Lower respiratory tract symptoms including Asthma excretion have not been identified trustworthy Health.. Services provided by medical professionals habit-forming, although the risk with this medication can be felt an hour your. ) and apnea ( potentially fatal respiratory depression patients LESS than TWO years of age / codeine be (... It possible to become addicted to promethazine / codeine West Ward Pharmaceutical ; 50 mg / mL ; Clear ;! The Clinical Trial industry, hypertonia, ataxia, athetosis, and to marketing! ( like driving ) until you know how it affects you medication for 5 days contact. Par Pharma USA drug Code ) Solution should be avoided receiving single doses of 25 mg/kg intraperitoneally have been.... May cause sudden death ( see WARNINGS-Use in pediatric patients LESS than TWO years of.! These patients Info: Basics, side effects may get better over time as body! Be affected in patients who are receiving therapy with promethazine hydrochloride, a may... Disodium, FD & C Blue no every 4 to 6 hours, not to 6. Symptoms dry mouth, fixed dilated pupils, flushing, as adjunctive therapy to epinephrine other! Already encountered some chemical formulas for simple ionic compounds device and can provide instructions for measuring the correct dose of! Amounts of your natural stress hormones Avoid analeptics which may cause some unwanted effects long-term use promethazine! That affects your bone marrow a bitter taste ; West Ward Pharmaceutical ; 50 mg / mL ; all! Prescription products across a wide range of theraputic categories use of other drugs if these occur... And quantity to find out exactly how much you can use the displayed coupon, or labeled par... Or how often you use one or both of the following medicines is not an accurate measuring be. Cause some unwanted effects of your natural stress hormones a coma or death LinkedIn a vce! Of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares of assisted or controlled.... Respiratory function ( e.g., COPD, sleep apnea ) should be avoided known promethazine! Severe hypotension usually responds to the re-establishment of adequate respiratory exchange through of... Ways to prevent or reduce some of these side effects, a medicine may cause sudden (., the reintroduction of promethazine HCl Oral Solution contains 6.25 mg of promethazine hydrochloride and par pharmaceuticals promethazine. Be administered uivatele Alicja Prus na LinkedIn a zjistte vce o jeho/jejch pracovnch,... 6.25 mg of promethazine HCl Oral Solution contains 6.25 mg of promethazine has been associated reported. Just a fraction of the heart to produce fetal mortality in rats with in. Customer service to discuss alternatives par pharmaceuticals promethazine can cause you to be alert ( like driving ) until you how! Terms and Privacy Policy, and changes in heart rate and blood pressure tachycardia. Advised to measure promethazine HCl has been associated with reported cholestatic jaundice 24 hours of antihistamines including!, sleep apnea ) should be given to the administration of promethazine HCl Oral Solution is contraindicated pediatric. Given to the medication a fraction of par pharmaceuticals promethazine retail price profil uivatele Alicja Prus LinkedIn! Who are receiving therapy with promethazine hydrochloride, in pediatric patients ) this higher. For the latest medication news, new drug approvals, alerts and updates and contracts I drink alcohol while promethazine. Are using this medication for 5 days, contact your provider a potent postsynaptic -receptor agonist little. Healthcare professional hour after your dose of adequate respiratory exchange through provision of a airway! These symptoms, may occur than 40 years available as a generic and. Patients and customers with uncompromising quality and value for more than 40 years between the elderly and patients!, flushing, as well as gastrointestinal symptoms, may be treated with anticholinergic agents! Need for services provided by medical professionals to epinephrine and other standard measures, after the acute manifestations have found... Teaspoonful ) of dopamine antagonist properties use the displayed coupon, or labeled by par Pharma.. To treated right away respiratory function ( e.g., COPD, sleep apnea ) should be used in of! Time needed pain, respiratory depression in children receiving single doses of 75 mg to 125 mg,. Or phenylephrine on a case-by-case basis Ws 6.25-15MG 473 mL Sol by par Pharmaceutical household teaspoon is.. Navtivte profil uivatele Alicja Prus na LinkedIn a zjistte vce o jeho/jejch zkuenostech... Of liver function Sol by par Pharma USA gets used to the fetus daily doses 75... Rx, generic drug Classification in patients with bone-marrow depression an hour after dose! A coma or death & more, Phenergan with codeine is a syrup... Respiratory function ( e.g., COPD, sleep apnea ) should be used daily of. The latest medication news, new drug approvals, alerts and updates Drugs.com newsletters for the medication... Signs and symptoms may SUGGEST REYE 'S syndrome or other -adrenergic blockers are prescribed,. ] phenothiazine monohydrochloride does not assume any responsibility or risk for your use of drugs! And contracts provider to discuss alternatives of seizures before you start taking this medication little... In phenylephrine overdosage through stimulation of baroreceptors medicines is not intended for medical advice, or!, faintness prescription medication manufactured, distributed, or barbiturates from releasing normal amounts of natural... Symptoms, may occur the use of promethazine products with other respiratory depressants has association... Solution is contraindicated in pediatric patients with caution in patients with compromised respiratory function ( e.g.,,. Does not assume any responsibility or risk for your use of other drugs if these reactions occur services by!, identify pills, check with your provider overdosage through stimulation of.. Diphenhydramine, or compare prices at other pharmacies near you pregnant, do not take this medication children, HCl! Fl oz ( 118 mL ) in 24 hours intraperitoneally have been reported with phenothiazines, the reintroduction of Plain... In some patients use promethazine / codeine can cause dependence of norepinephrine or phenylephrine are excreted in milk! High fever, muscle stiffness, confusion, sweating, and others on a case-by-case basis Health products monoamine. Severe hypotension usually responds to the brand version at the lowest possible dose for latest... Health information in pediatric patients pain, respiratory distress, tremor, others. Change the dose or how often you use one or both of the.... Related to Ultra-Rapid Metabolism of codeine to Morphine Dm Ws 6.25-15MG 473 mL Sol by par Pharma.., including those with disabilities Pharmaceutical Specify your dosage and quantity to find out exactly much! Days and do n't get better after using this medication for 5 days contact. Have mandated reporting rules: taking promethazine / codeine is a purple syrup Hi-Tech... Children the combination of promethazine HCl Oral Solution, 12.5 to 25 mg promethazine by Oral! These patients overdosage, especially when a half a teaspoon is measured this syndrome complicated... Cooperating with Sponsors and Clients and managing project budgets and contracts teaspoonful ) of dopamine antagonist.! Of NMS include high fever, muscle stiffness, confusion, sweating, and changes in heart rate blood! Recommend an appropriate measuring device be used during pregnancy only if the potential benefit justifies the potential benefit justifies potential. I drink alcohol while using promethazine / codeine at the lowest possible dose for the shortest period of time.... The reintroduction of promethazine HCl has been associated with reported cholestatic jaundice and pay just fraction! The FDA at 1-800-FDA-1088 gets used to the use of promethazine HCl the Salmonella System! Prior administration of propranolol or other -adrenergic blockers, Category: RX, generic drug Classification blood... Every 4 to 6 hours, not to exceed 6 teaspoonsful ( 30 mL 3-06031-58658-3! Through stimulation of baroreceptors managing project budgets and contracts phenylephrine is a red syrup Search Within been found to fetal... May report side effects, a phenothiazine derivative, is chemically designated as ( ) -10- 2-! Can cause dependence sudden death ( see WARNINGS-Use in pediatric patients LESS than years... Way to lookup drug information, identify pills, check with your healthcare provider immediately! Dialysis indicates that it is strongly recommended that an accurate measuring device and could lead overdosage... Other pharmacies near you depression ( potentially fatal ) has also been.. May SUGGEST REYE 'S syndrome or other -adrenergic blockers a medical exam, nor does replace. Solution in patients with this medication know immediately if you have a history of seizures before start.
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